Hyperexcitability of rat thalamocortical networks after exposure to general anesthesia during brain development.

Changes in membrane and synaptic properties of thalamocortical circuitry caused by hydrogen peroxide.

Free radical (FR) production was linked to the generation of epileptiform activity. We performed electrophysiological recordings in rat thalamocortical slices to investigate the effects of FRs on the intrinsic and synaptic properties of thalamic and cortical neurons. Whole cell recordings from identified cortical pyramidal neurons and thalamic neurons of the ventrobasal nucleus revealed that ex...

Effects of Atorvastatin on the Hypertension-Induced Oxidative Stress in the Rat Brain

Background: It is well known that the development of brain oxidative stress is one of the most serious complications of arterial hypertension that evokes brain tissue damage. The aim of this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (HTN) rats. Methods: Experiments were performed...

The Effect of Noise Pollution Exposure during Pregnancy on Long Term Potentiation Induction in Pyramidal Neurons of Hippocampus CA1 area in Male Rat Offsprings

Background: It is believed that cognitive processing is easily disturbed by incompatible environmental stimulations. Many studies have shown that prenatal stress affects fetal brain development. The aim of this study was to evaluate the effect of noise pollution exposure during conception period on neural activity of hippocampus CA1 area in male rat offspring. Methods: Four groups of rats inclu...

Neurotrophic Factor Slices of Adult Rat After Exposure to Brain-Derived Hyperexcitability in Combined Entorhinal/Hippocampal

The Effect of Increased Electrical Field Strength of 950 MHz Waves on the EPSP Slope

Introduction: Over the last decade, exposure to electromagnetic waves due to base station antennas has increased. This study was planned to evaluate the effects of different electrical field strengths with 950 MHz waves of the GSM mobile phone system on the excitatory postsynaptic potentiation (EPSP) slope of the dentate gyrus long-term potentiation (LTP). Material and Methods: Twenty four naiv...